In Vivo Effects of Single Intra-Articular Injection of 0.5% Bupivacaine on Articular Cartilage
نویسندگان
چکیده
منابع مشابه
Evaluation of intra-articular injection of bupivacaine in combination with morphine, methylprednisolone, or alone on pain after knee arthroscopy
Background and Aims: Knee arthroscopy is used to diagnose and treat intra-articular lesions. The control of acute pain after arthroscopy requires the use of a method with the least side effects and most efficacies. This study aimed to compare the sedative effect of bupivacaine in combination with morphine, methylprednisolone, or alone in knee arthroscopy after intra-articular injection. Materi...
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We have investigated the effects of intra-articular (i.a.) administration of ketorolac in the rat knee joint. Thirty Sprague-Dawley rats were given 0.25 ml of a standard preparation of ketorolac trometamol (10 mg ml-1) by injection into the right knee joint and 0.25 ml of 0.9% physiological saline solution by injection into the left knee as a control. Ten rats were killed at 24 h, 10 at 48 h an...
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BACKGROUND Intra-articular (IA) corticosteroid therapy has been used for the treatment of inflammation and pain in the knee since the 1950s. PURPOSE To review the current literature on the effects of IA corticosteroids on articular cartilage. STUDY DESIGN Systematic review. METHODS A MEDLINE and SCOPUS database search was performed, and studies were selected for basic science and clinical...
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OBJECTIVES Recent studies have shown that systemic injection of rapamycin can prevent the development of osteoarthritis (OA)-like changes in human chondrocytes and reduce the severity of experimental OA. However, the systemic injection of rapamycin leads to many side effects. The purpose of this study was to determine the effects of intra-articular injection of Torin 1, which as a specific inhi...
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ژورنال
عنوان ژورنال: The Journal of Bone and Joint Surgery-American Volume
سال: 2010
ISSN: 0021-9355
DOI: 10.2106/jbjs.i.00425